Professor of Therapeutics-Cardiology at the University of Lorraine. Doctor in Medicine, Doctor in Human Biology (PhD), Clinical Pharmacology (University of Lyon and Oxford).

Current functions

Consultant at the Clinical Investigation Centre (CIC) Inserm.

Main Contributions

Establishment of a Cardiac Insufficiency care network in Lorraine. Author of major advances in the field of mineralocorticoids, leading to changes in therapeutic practices (IA Recommendations) to prolong survival in heart failure.

Areas of research

Heart failure, Aldosterone, Fibrosis, Biomarkers, Clinical trials, Hypertension. He coordinates several EU FP7: Heart failure Omics and AGEing (HOMAGE), FIBRosis as a TARGET in Heart Failure (FIBROTARGETS), Franco-German ANR. FOCUS-MR. WP leader EU FP7 (The MEtabolic Road to DIAstolic Heart Failure (MEDIA), FHU CARTAGE and RHU FIGHT-HF, Nancy, he is the coordinator of the Contrat de Plan Etat Région Lorraine (CPER) “Innovations Technologiques, Modélisation et Médecine Personnalisée”.

He holds several patents in the biomarker field. Co-founder of “CardioRenal, Sarl”, a telemedicine start-up. Founder and organizer of the CVCT forum “Global CardioVascular Clinical Trialists Forum”. ( with Inserm, US-NHLBI, EMA and FDA, since 2003, and now in Washington DC.


In 1981, he obtained the CNRS prize for young scientists in clinical pharmacology for his research in cardiovascular pharmacology1.
In 1983, he received the Paul Neumann Prize in Clinical Pharmacology1.
In 2014, he won the Paul Milliez Prize for his work on hypertension11.
In 2015, he became the first doctor in Tunisian history to be listed among the most cited researchers by Thomson Reuters12. It maintains its place in this ranking in 2016 and 201712.

Learned Societies

Former President of the French Society of High Blood Pressure (2007-2008), Former President of the Working Group Pharmacology and Drug Therapy of the European Society of Cardiology (2008-2010), he also participates in numerous Editorial Committees of scientific journals.

As of 30/10/2016, he is the author of 573 publications, 81218 citations, and his Hirsch Index is 85.