Protocols tested since 1995


Patients and healthy volunteers


Original publications

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The Pierre DrouinMultidisciplinary Clinical Investigation Centre (CIC-P 1433) of the Nancy CHRU is the interface between fundamental research and applied medical research. Its objective is to produce new scientific and medical knowledge in the cardio-renal field, in compliance with ethical and legal rules.

It was created in 1995 on the initiative of Professor Pierre Drouin* and Professor Faiez Zannad. It is currently under the joint supervision of the CHRU,INSERM and the University of Lorraine. This module coordinates the Cardiovascular Thematic Network.

Clinical investigation centres (CICs) are clinical research infrastructures made available to investigators to carry out their clinical and health research projects.

The themes of the CIC-P :


Worktop 1

Drug testing



Heart failure

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The CIC-P works in compliance with regulations: the Helsinki declaration, European directives, French laws in force and good clinical practice.

The operation of the CIC-P is governed by its own procedures and those of the University Hospital.

In order to produce quality work, a quality assurance department has been set up. This department ensures that these regulations and procedures are properly applied.

The quality assurance department, under the responsibility of Prof. Rossignol, is responsible for drafting and revising procedures and for training staff in them by various means (meetings, preparation of brochures, review sessions). In addition, the application of and compliance with the procedures are monitored by the signing of a commitment to read the procedures, by carrying out internal audits and by knowledge control sessions.

Staff training on the regulatory changes and the resulting practical changes is also a priority for the CIC-P.

Each member of the CIC-P is therefore responsible at his or her level for ensuring that his or her activity is part of a quality assurance process, which makes it possible to ensure that the CIC-P works with a view to developing studies of the highest scientific quality.